ISSN: 2329-8901
Department of Microbiology, East Carolina University, Greenville, North Carolina, USA
Review Article
Probiotic Therapy as a Complementary Treatment for Patients with COVID-19 and Other Upper Respiratory Tract Infections
Author(s): Connie L. Brenstuhl*
This literature review is aimed at assessing and summarizing relationships between the state of the microbiome and
susceptibility to respiratory tract infections including COVID-19. It explores using probiotic therapy for patients
infected with COVID-19, to improve outcomes, lessen the severity of symptoms, or prevent infection entirely. The
coronavirus COVID-19 is known scientifically as severe acute respiratory syndrome coronavirus-2. The virus's binding
sites for cell entry, the angiotensin-converting enzyme-2, are found in high concentrations in both respiratory and
gut tissues. Probiotics may inhibit angiotensin-converting enzyme-2 receptor activity, thereby blocking viral entry
into the cell. COVID-19 infection with alpha and delta variants has manifested clinically both in severe respiratory
and gastrointestinal symptoms. The impact on the host’s micr.. View More»
DOI:
10.35248/2329-8901.22.10.269