ISSN: 2165-8048
+44 1300 500008
Independent Research, Bucharest, Romania
Review Article
Potential Approach of Hepatitis B by Inhibiting MDSC to Obtain Control of the Immune System.
Author(s): Cosmin Constantin Oprea*
Purpose of Review: Hepatitis B virus infection and the immune response in babies and adults.
Findings: The presence of myeloid-derived suppressor cells (MDSCs) in new-borns makes Hepatitis B to become
chronic over years with both antigens present in the blood, HBs and HBe, the immune system not being able to
recognize the infection in the first years of life. The expansion of myeloid-derived suppressor cells (MDSCs) allows
the immune system to maintain the infection with Hepatitis B, although the patient reaches adult age, because
myeloid-derived suppressor cells (MDSCs) are responsible for the disfunction of the immune system and not the
virus itself. Our goal is to show what is maintaining T cell exhaustion in hepatitis B, why this is happening and what
is responsible for this.
MDSC is responsible for chronic Hepatiti.. View More»
DOI:
10.35248/2165-8048.21.s6.006