Journal of Clinical Toxicology
Open Access

Department of Pediatrics, University of California Los Angeles Medical Center, Division of Nephrology, Los Angeles, CA, USA

Biography

Dr. Cristina M. Farkas Skiles currently working in University of California Los Angeles Medical Center, Division of Nephrology, Los Angeles, CA, USA in the department of Pediatrics his publications are Baclofen Neurotoxicity in a Pediatric Patient on Peritoneal Dialysis

Publications

• Case Report   
  Baclofen Neurotoxicity in a Pediatric Patient on Peritoneal Dialysis
  Author(s): Cristina M. Farkas Skiles*, Michael D. Levine, Komal A. Patel and Rachana Srivastava
  
  We describe a 2-year-old patient with End Stage Kidney Disease (ESKD) on Continuous Cycling Peritoneal Dialysis (CCPD), gastroesophageal reflux disease, gastric tube dependence who presented with hypotension, confusion and lethargy 1 day after initiating oral baclofen for chronic vomiting. Sepsis work up and baclofen level were sent, later showing baclofen level of 0.55 mcg/ml. The patient required norepinephrine and CCPD for 24 hours before returning to baseline. CCPD was continued for 33 hours and he was discharged home at baclofen level of 0.25 mcg/mL... View More»
  

  Abstract PDF