Journal of Clinical Trials
Open Access

Department of endocrine ophthalmology, Medical University, Sofia, Bulgaria

Publications

• Research Article   
  Complications after Anti-Vascular Endothelial Growth Factor Treatment of Patients with Wet Age-Related Macular Degeneration
  Author(s): Christina Vidinova*, Dafina Antonova and Kalin Vidinov
  
  Anti-Vascular Endothelial Growth Factor (VEGF) therapy is the leading treatment strategy for Age-related Macular Degeneration (AMD). Although this treatment generally improves VA of the affected patients, its prolonged application can lead to serious complications. Purpose: The purpose of our study is to outline the possible long term complications of anti-VEGF treatment in AMD patients and to outline eventual ways to avoid some of them. Methods: In our prospective study 42 patients with wet AMD were enrolled. They all underwent a complete ophthalmological examination including Visual Acuity (VA), fundus photography, structural Optical Coherence Tomography (OCT) (Revue, Optovue) and OCT-A (Angiophlex, Zeiss). All of the patients were treated with aflibercept (Eylea)-in the Treat and Extend regiment for a period of 2 y.. View More»
  DOI: 10.35248/2167-0870.22.12.498

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