Journal of Agricultural Science and Food Research
Open Access
ISSN: 2593-9173
ISSN: 2593-9173
Department of Products Developement Programme, National Horticultural Researh Institute, P.M.B. 5432, Idi-Ishin, Ibadan, Oyo State, Nigeria
Research Article
Phytochemical Profiling and Molecular Docking Investigation of Avocado (Persea americana mill. Cultivar Hass) Leaves and Seeds: Implications for Antioxidant Activity and Health Benefits
Author(s): Olufemi Temitope Ademoyegun, Rabiat Shola Ahmed, David Olamide Raphael, Balikis Oluwakemi Mustapha and Shina Salau*
Despite the rising interest in avocado leaves and seeds health benefits, little or no research has been conducted on both their phytochemical profiles in conjunction with molecular docking investigations, particularly in relation to its antioxidant activity. Utilizing phytochemical screening molecular docking and Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) research. This study investigates the antioxidant properties of Avocado Leaves (AVL) and Avocado Seeds (AVS). Results show that AVS has a high presence of flavonoids (+++), terpenoids (+++), but a low presence of phenols (+), while AVL has a high presence of tannins (+++) and phenols (++). Molecular docking studies validate two AVL (L01 and L02) and two AVS (S02 and S03) compounds based on binding affinity and interactions with 2 Retrograde Urethrogram (RGU).pdb, 3.. View More»
DOI:
10.35248/2593-9173.24.15.168