ISSN: 2165-8048
+44 1300 500008
Department of Dermatology, Norris Comprehensive Cancer Center, Keck School of Medicine of USC, USA
Case Report
Explosive Granulomatosis with Polyangiitis Mimicking Infective Endocarditis
Author(s): Lisa Shue, Maggie Chow, Brandon Cohen and David Peng*
Background: Granulomatosis with polyangiitis (GPA) is a rare systemic disease that causes necrotizing granulomatous inflammation of small- and medium-sized blood vessels. Infective endocarditis (IE), which is a disease due to infection of the innermost surface of the heart, is pathophysiologically distinct from GPA and yet these two entities can manifest in strikingly similar ways.
Case presentation: We report a case of a 46-year-old male whose presentation and history were strikingly suggestive of IE but was ultimately diagnosed with GPA. Originally, he presented with fever, oral ulcers, and purpuric lesions on the extremities. The patient had a history of illicit drug use and had recently undergone a dental procedure one week prior to presentation, which were classic risk factors for IE. His fever and respiratory difficulty were unresponsi.. View More»
DOI:
10.35248/2165-8048.19.9.302