Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Department of Graduate Studies in Biomedical Sciences, Federal University of Fronteira Sul (UFFS), Chapeco, Santa Catarina, Brazil
Research Article
Exercise-Mediated Immune Protection in Chronic Kidney Disease Decreases Infection and Severe Evolution of COVID-19
Author(s): Josiano Guilherme Puhle, Vanessa da Silva Corralo, Adinei Abadio Soares, Joao Vitor Kroth, Mariana Munhoz Gallina, Matheus Goncalves Cavasin, Vinicius Ansolin, Danieli de Cristo, Angela Makeli Kososki Dalagnol, Debora Tavares de Resende e Silva*, Gabriela Vidotto Cavallieri and Renata Calciolari Rossi
It is constantly sought to understand the different mechanisms of action of the immune system to establish potential
efficient therapeutic targets for different clinical situations. Thus, the present study aims to expand the knowledge
about the protective effect of physical exercise on the immune system of patients with chronic renal failure,
associating it with the incidence of infection by COVID-19. The present study was based on a narrative systematic
review of the literature and understands, elucidate, and discuss the subject. The main result found was that regular,
moderate-intensity exercise modulates immunological parameters in CKD patients, evidenced by decreased
inflammatory factors such as Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Interleukin-18 (IL-18) and Tumor Necrosis
Factor-α (TNFα), and increased Interleukin-10 (IL-10) and.. View More»
DOI:
10.35248/2155-9899.23.14.692