ISSN: 2329-6631
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Department of Pharmaceutical Chemistry, Global Institute of Pharmaceutical Education and Research, Affiliated to Uttarakhand Technical University, Kashipur, Uttarakhand, India
He studied in Global Institute of Pharmaceutical Education and Research, Kashipur established in 2009 is a premier institution in the field of pharmaceutical sciences for fulfilling the emerging need of the society and country and to make India a World leader in the field of pharmaceutical science.
Research Article
Control of Aedes aegypti Mosquito Vector by Attempting QSAR Modeling on Phenoxyacetamide-Based Inhibitors to Target AChE1
Author(s): Aaliya Naaz, Mohit Kumar, Ankita Sharma, Deepak Teotia, Sisir Nandi* and Mridula Saxena
Female Aedes aegypti and Anopheles gambiae mosquitoes are living vectors liable for transmitting many parasitic and dreadful viral diseases. The major target is acetyl cholinesterase (AChE) 1 enzyme for the parasite transmission. Anopheles gambiae carries AgAChE1 enzyme responsible for the malaria parasite whereas Aedes aegypti carries AaAChE1 enzyme that injects dengue, yellow fever, Zika, and chikungunya viruses to the healthy individuals. These vector-borne infections are now a major public threat. Deforestation and global warming may cause drastic change of the climate which causes vector-borne disease to re-emerge worldwide. Control of mosquito vector saves many lives. One of the mechanisms to kill the mosquito vector is to use insecticides such as chlorinated hydrocarbons, organophosphates, carbamates, and pyrethroids recommended by the World .. View More»