Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Department of Cardiology, Federal University of São Paulo, São Paulo, Brazil
Research Article
The End of Repeated Reoperations for Degenerated Bioprosthesis? Hydrodynamic In-Vitro Analysis for Sequential Valve-in-Valve Feasibility
Author(s): Caio Cesar Cardoso*, Diego Felipe Gaia, José Honorio Palma and José de Lima Oliveira Jr
Objective: To develop a therapeutic guide for the implantation of Braile Inovare transcatheter valves within valvein-valve sets (including valve-in-valve-in-valve and sequential valve-in-valve configurations), based on hydrodynamic testing. The guide aims to establish therapeutic limits and recommend optimal sizes for transcatheter valves.
Materials and Methods: Hydrodynamic testing was performed using the pulse duplicator to measure the effective orifice area in square centimeter and the mean transvalvular gradient in millimetres of mercury of various valve sets. The tests adhered to Food and Drug Administration (FDA) and International Organization for Standardization (ISO) regulations, specifically ISO 5840. For sequential valve-in-valve testing, each selected valve-in-valve set was evaluated with a transcatheter valve s.. View More»
DOI:
10.35248/2155-9880.24.15.912