Clinical Pediatrics: Open Access
Open Access

Department of Pediatric, Edward Via College of Osteopathic Medicine (VCOM)-Carolinas, Spartanburg, South Carolina 29303, United States

Publications

• Case Report   
  Atypical Antidepressant Toxidrome: A Case Report and a Proposed New Toxicity Syndrome
  Author(s): Hanna S. Sahhar*, Lauren Bailey and Erica Rubin
  
  We report a case of intentional bupropion overdose in an adolescent female who presented with seizure, altered mental status, tachycardia, elevated anion gap, and hyperglycemia. Bupropion is an Atypical Anti-Depressant (AAD) that is typically used to treat major depressive disorder, seasonal affective disorder, and selective serotonin reuptake inhibitor-induced sexual dysfunction. Though there are documented cases of bupropion and other AAD overdose cases in pediatric literature with established presentations, AAD toxicity can still be challenging to recognize. Patients presenting with bupropion toxicity often require high level life sustaining care including airway stabilization and mechanical ventilation, vasopressor and inotropic support, and even extracorporeal membrane oxygenation, making early clinical identification of this toxicity especially important. AAD toxicity should be .. View More»
  DOI: 10.35248/2572-0775.22.7.220

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