Journal of Chromatography & Separation Techniques

Journal of Chromatography & Separation Techniques
Open Access

ISSN: 2157-7064

+44 1300 500008

Erwin Gelfand

Department of Chemical Engineering, University of Cambridge, Cambridge, UK

Biography

Dr. Erwin Gelfand is a researcher in the Department of Chemical Engineering at the University of Cambridge, UK. His work focuses on advancing protein enrichment techniques, particularly through the development of novel polyhedral silsesquioxane-based capillary monoliths for micro-Immobilized Metal Affinity Chromatography (μ-IMAC). This innovative approach aims to enhance the isolation and purification of histidine-tagged proteins, which are crucial in biochemical research and biotechnological applications. In his recent publication, "Advancing Protein Enrichment with Novel Polyhedral Silsesquioxane Capillary Monolith in μ-IMAC," Dr. Gelfand details the synthesis and functionalization of these capillary monoliths. The study emphasizes the integration of polyhedral silsesquioxane into the polymer matrix via thiol-methacrylate polymerization, resulting in monoliths with enhanced mechanical stability, increased porosity, and expanded surface area. These improvements collectively enhance chromatographic performance, offering a promising tool for efficient protein purification. Dr. Gelfand's research contributes significantly to the field of chemical engineering, particularly in the development of advanced materials for protein purification. His work holds promise for applications in proteomics research, biotechnology, and biomedical sciences, paving the way for improved protein purification methodologies and enhanced understanding of biological systems.

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