ISSN: 2155-6148
Dr, Department of Anaesthesiology, Kashmir Institute of Medical Sciences, Jammu and Kashmir, India
Case Report
Anaesthetic Management of a Patient with Congenital Factor VII Deficiency Undergoing Spine Surgery for a Tethered Cord: A Case Report
Author(s): Faizah Mufti. Sher E*, Bashir Ahmad Dar, Majid Khan and Shehla Bashir
Background: Congenital factor VII deficiency is a rare bleeding disorder that can lead to excessive bleeding during
the intra-operative period and sometimes also during the postoperative period, which can lead to overall increase in
morbidity and mortality. These patients may present with different clinical scenarios which may vary from being
asymptomatic to bleeding that can be mild to life threatening. The recombinant form of activated factor VII (rFVIIa,
NovoSeven®) has been used in the management of hemorrhage in the patients with factor VII deficiency.
Case: Patient’s factor VII levels were determined. We administered recombinant factor VIIa, two hours prior to
surgery. Repeat sample for coagulation profile was taken 1 hour after administration. Post operatively dose was to be
repeated 4 hourly until adequate .. View More»