Immunogenetics: Open Access
Open Access

Department of Gastroenterology, Jinan University, Guangzhou, 510630, China

Publications

• Research Article   
  Multiple Sclerosis and Health Outcomes: A Comprehensive Analysis Based on Observational Meta-Analyses
  Author(s): Lianli Shen, Fang Long, Lixian Zhong, Sisi Chen, Lichen Li and Shaohui Tang*
  
  Purpose: The previous meta-analyses have illustrated that Multiple Sclerosis (MS) is correlated with multiple health outcomes. We designed an umbrella meta-analysis to evaluate the breadth, validity and presence of biases of the associations of MS with diverse health outcomes. Methods: We searched three databases (PubMed, Web of Science and Embase) to recalculate the summary effect sizes, 95% CI, heterogeneity and small-study effects in the included meta-analyses. For each meta-analysis, we assessed the quality with AMSTAR2 and graded the epidemiologic evidence. Results: A total of 28 articles comprising 84 unique meta-analyses were included in this study. Among the 84 unique outcomes, 52 unique outcomes had significant associations (p<0.05). Only 6 outcomes (Inflammatory Bowel Disease (IBD), Ulcer.. View More»
  DOI: 10.35248/IGOA.24.9.228

  Abstract HTML PDF