ISSN: 2329-6917
+44 1300 500008
Department of Biomedicine, Pontifical Catholic University, Goias, Brazil
Review Article
Angiogenesis in Leukemias: A Review
Author(s): Susy Ricardo Lemes*, Luciana Cardoso Marinho, Katia Karina Veroli de Oliveira Moura, Fatima Mrue and Paulo Roberto de Melo-Reis
Objectives: This study aimed to investigate the influence of the angiogenic process on the development of leukemias.
Methods: A systematic review was performed based on 230 published manuscripts, 90 of which between 1995 and
2016, involving in vitro and in vivo experiments and reviews of the angiogenic process, types of leukemias and
angiogenic factors involved in the origin of tumors. Searches were carried out in the Latin American and Caribbean
Literature in Health Sciences (LILACS), Scientific electronic library online (Scielo), Scopus and Pubmed databases,
among others. We excluded articles that did not report the relationship between angiogenesis and leukemias or
angiogenic factors and leukemias.
Results: Evidence suggests that angiogenic factors such as FGF, HGF, TGF, TNF, HIF-1, .. View More»
DOI:
10.35248/2329-6917.23.11.353