Journal of Developing Drugs
Open Access

Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria

Publications

• Research Article   
  Formulation Studies on Hibiscus Sabdariffa (HS) Aqueous Extract
  Author(s): Y.J. Oyeniyi* and F.B.O. Mojiminiyi
  
  Background: Hibiscus sabdariffa L. family Malvaceae is a perennial herbaceous medicinal shrub widely cultivated for its proven anti-hypertensive property Objectives: The focus of this investigation is to formulate the aqueous extract of HS as oral tablets for accurate dosing and to ease the administration of the aqueous extract. Method: Five formulations of HS granules were prepared by wet granulation technique and thereafter the flow characteristics of the granules were assessed through, angle of repose, Hausner’s ratio, density measurements, moisture content and compressibility index determinations. Heckel and Kawakita analyses were however employed to study HS granules compactability, while the United State Pharmacopeia 2012 (USP) quality control tests were used to investigate the tabletting properties... View More»
  

  Abstract PDF