Journal of Chromatography & Separation Techniques
Open Access

Department of Chemistry, University of Engineering and Technology, Lahore, Punjab, Pakistan

Publications

• Research Article   
  Comparative Stability of Different Brands of Esomeprazole Magnesium Trihydrate of Enteric-coated Pellets Capsules
  Author(s): Fozia Bibi*, Syeda Rubina Gilani, Zubia Gulzar and Nafeesa Gul
  
  The aim of study is to determine the stability of Esomeprazole magnesium trihydrate under environmental conditions and Accelerated stability chamber. The drug products of esomeprazole enteric-coated pellets are more sensitive to environmental factors like heat, humidity, and light. These factors affect the stability of the product if not stored under the necessary condition. A stability study of enteric-coated pellets of esomeprazole magnesium trihydrate was performed following the USP method. Stability testing was performed for a new pharmaceutical product. The accelerated test was performed for the evolution of the stability at climate change like 40°C ± 2°C and 75 ± 5% Relative Humidity (RH). The newly formulated brands were kept in the accelerated chamber (40 ± 2°C/75 ± 5% RH) for six months. After three and six months, products were analyz.. View More»
  DOI: 10.35248/2157-7064.22.S1.005

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