Journal of Clinical Toxicology
Open Access

Department of Pharmacy, Fudan University, Shanghai, China

Biography

Dr. Gang Wei is affiliated with the College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, where Dr. Gang Wei is currently working as an Associate Professor. Dr. Gang Wei has authored and co-authored several national and international publications and also working as a reviewer for reputed professional journals.

Publications

• Research Article   
  In vitro Inactivation of SARS-Cov-2 by Povidone-Iodine In situ Gel Forming Solution
  Author(s): Bo Liang*, Xudong Yuan, Gang Wei, Wei Wang, Ming Zhang, Haizhou Peng, Juan C. Hernaiz-Leonardo, Amin Javer, Michelle Mendenhall, Justin Julander, Sammi Huang, Hany Michail, Yong Lu, Qi Zhu and John Baldwin
  
  Background: Povidone Iodine (PVP-I) nasal solutions are effective against the SARS-CoV-2 virus, but are cleared rapidly from the nasal cavity, limiting its use. PVP-I gel forming solutions can circumvent this problem due to their higher viscosity and prolonged clearing time. Objective: Characterize the in vitro virucidal activity of long-acting PVP-I compositions developed using an in situ gel forming technology against the SARS-CoV-2 virus and test its safety using a rat model. Methods: We tested different dilutions of the PVP-I gel forming solution– full concentration, 90%, 50%, 28% and 9% of the original formulation concentration – at varying exposure times to assess virucidal activity against SARSCoV- 2 in VERO76 cells infected. Virucidal activity was recorded as the reduction of v.. View More»
  DOI: 10.35248/2161-0495.21.s18.002

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