Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Department of Pharmacy, University of Salerno, Italy
Gasparri F works at Department of Pharmacy (DIFARMA), University of Salerno, Italy. The author has recently published a manuscript entitled 'Clinical Evidence on a New Thymol and Zinc-Based Cleanser for Feminine Hygiene in a Double-Blind Controlled Randomized Study' with us.
Research
Mucoadhesive Properties of a New Intimate Hygiene Cleanser against
Vulvovaginal Candidiasis
Author(s): Benvenuti C*, Gasparri F and Zanardi A
Objective: Performance of feminine cleansers can be improved by increasing antimicrobial potency and favouring the prolonged contact on vulvo-vaginal mucosa of active ingredients, that permits the increase of the persistence of their activity, and consequently of their efficacy.
The presence of specific polymers in topical formulations allows the cleansing solution to adhere to mucosal substrates.
The associations of xanthan gum with lambda carrageenan from Chondrus crispus has a high mucoadhesive potential. The aim of our study was to evaluate the mucoadhesive potential and the safety of an innovative cleanser for feminine hygiene (SA3) compared with a reference cleanser (SA) in a double-blind design.
Material and Methods: The cleansers were provided at dilutions: the reference product containing thymol from Thymu.. View More»