Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Department of Obstetrics and Gynecology, Ex-Rotunda-A Centre for Human Reproduction, Mumbai, India
Mini Review
An Update on Factors that Enhance the Chances of Discrimination on Constitutional Delay of Growth and Puberty from Congenital Hypogonadotropic Hypogonadism: Emphasis on Role of INSL3
Author(s): Kulvinder Kochar Kaur*, Gautam Nand K Allahbadia and Mandeep Singh
Delayed Puberty (DP) is practically correlated with the presence of either Constitutional Delay of Growth of Puberty (CDGP), or Congenital Hypogonadotropic Hypogonadism (CHH). Although lots of so called “red flags” are associated with CHH frequently, they usually get sidelined by most physicians. Hence assessment of various markers like Insulin like peptide 3 (INSL3) as well as Inhibin B (INB) has been done in the form of probable markers regarding discrimination of CDGP along with CHH respectively, either in basal state or subsequent to Gonadotropin Releasing Hormone a (GnRHa) stimulation. Insulin like peptide 3(INSL3) represents a product that gets liberated by Leydig cells along with is getting considered in the form of probable marker regarding discrimination of CDGP along with CHH besides the commonly used INB. It is significant to differentiate the .. View More»
DOI:
10.35248/2375-4508.23.11.288