Internal Medicine: Open Access
Open Access

Department of Cardiology Arthritis Research UK Epidemiology, Manchester University, Manchester, UK

Publications

• Review Article   
  Pathophysiology of Bone and Cardiac Involvement in Spondyloarthropathies: The Indispensible Value of Magnetic Resonance Imaging
  Author(s): Sophie I Mavrogeni*, Ioannis Nikas, Maria Bonou and George D Kitas
  
  Spondyloarthropathies include a group of inflammatory arthritides encompassing Ankylosing Spondylitis (AS), reactive arthritis, arthritis/spondylitis associated with Psoriatic Arthritis (PSA) and arthritis/spondylitis associated with Inflammatory Bowel Diseases (IBD). In Spondyloarthropathies, inflammation can act either by promoting atherosclerosis or by increasing the effect of conventional CV risk factors. The incidence of Cardio Vascular (CV) disease in AS is 10%-30% and includes aortic valve regurgitation, aortitis, Atrio Ventricular (AV) and/or bundle branch block. In Psoriatic Arthritis and IBD, there is increased risk of CV events, because high levels of cytokines promote atherosclerosis. Furthermore, the persistence of systemic inflammation promotes the development of myocardial inflammation. Magnetic Resonance Imaging (MRI) can identify inflammation in the early st.. View More»
  DOI: 10.35248/2165-8048.21.s8.004

  Abstract HTML PDF