Anesthesia & Clinical Research
Open Access

Department of Clinical Research, University of Science and Technology of China, Hefei, China

Publications

• Research Article   
  PCEA Reduced the Expression of Regulatory T Cells in Elderly Patients Undergoing Open Colectomy
  Author(s): Haixia Shi*
  
  Background and aim: Open colectomy is associated with postsurgical pain. Regulatory T cells (Tregs) are crucial in the recovery and metastasis of tumor cells, infection and immune response. To compare the expression of Tregs on Patient-Controlled Epidural Analgesia (PCEA) and Patient-Controlled Intravenous Analgesia (PCIA) in elderly patients undergoing open colectomy. Methods: From September 2015 to October 2017, 100 elderly patients were scheduled for elective open colectomy with general anesthesia. Patients were randomly divided into the PCEA and PCIA group. Detected CD4, CD25 and CD27 by flow cytometry and calculated the proportion of CD4+ CD25+ CD127- Tregs in CD4+ T lymphocytes. Recorded Visual Analog Pain Score (VAS) on the first and second days postoperatively. Also, recorde.. View More»
  

  Abstract PDF