ISSN: 2329-8936
Department of Molecular Biology and Genetics, Istanbul Arel University, 34537, Buyukcekmece, Istanbul, Turkey
Research Article
A Promising Strategy Against SARS-CoV-2 Infected Patients: Antisense
Therapy
Author(s): Hasan Cubuk*
As of July 25-2020, 643,412 people in more than 215 countries have been victims of the new type of coronavirus,
SARS-CoV-2. Thereby, there is a huge effort to develop a strategy to treat, and or prevent people from SARS-CoV-2
infection. Those efforts could be mainly categorized as drug repurposing, anti-SARS-CoV-2 antibodies from people
who recovered, and vaccines. However, there is currently no specific treatment available against SARS-CoV-2 infected
patients. That`s why many new approaches and ideas are still studied every day for the treatment of SARS-CoV-2
infected patients. Antisense therapy is one of these promising approaches to target SARS-CoV-2 genomic RNA
specifically and inhibit its activity upon incorrect viral RNA processing. In this study, Antisense Oligonucleotide
(ASO) candidates targeting SARS-CoV-2 genomic RNA were designed. High-scored ASOs with.. View More»
DOI:
10.35248/2329-8936.22.8.119