Journal of Clinical Toxicology
Open Access

Clinical Pharmacology and Toxicology Unit, Schneider Children’s Medical Center, Petah Tiqva, Israel

Publications

• Case Report   
  Neurologic Involvement in a Young Child with Paraquat Poisoning Treated with Rapamycin
  Author(s): Inbar Zioni*, Adi Glass, Yedidia Bentu, Patrick Stafler, Liora Kornreich, Gilat Livni and Havazelet Yarden-Bilavski
  
  Parquet (1, 1’-dimethyl-4-4’-bipyridinium dichloride), an agricultural herbicide, is highly toxic to humans. A 78% mortality rate previously reported for the ingestion of 20% Paraquat commercial preparation. No specific antidote is available; hence cases of poisoning require aggressive decontamination. We report an unintentional ingestion of a 15- months-old male who developed severe neurologic manifestations. Clinical experiences were seen; in vitro and animal models often demonstrate a lack of consistency with clinical response... View More»
  DOI: 10.35248/2161-0495.21.11.493

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