ISSN: 2161-0487
+44 1478 350008
Department of Psychiatry and Mental Health, Fauji Foundation Hospital, Rawalpindi, Punjab, Pakistan
Review Article
Vitamin D Deficiency and its Association with Depression in Under 18s: The Intricacies of Sunlight and Darkness
Author(s): Hayat Khan*
Vitamin D receptors are present in areas of the brain involved in mood regulation, such as the hippocampus
and prefrontal cortex. It is suggested that vitamin D may modulate the synthesis and release of neurotransmitters,
including serotonin, dopamine, and norepinephrine, which play important roles in mood regulation and are
implicated in depression. Vitamin D also has anti-inflammatory properties and can influence immune system
functioning. Chronic inflammation has been linked to the development of depression. Vitamin D may help regulate
the immune response, reducing inflammation and potentially mitigating depressive symptoms. The deficiency of
this vitamin has been previously thought to be not as common as recognized now. This review looked at several
studies to explore the association of vitamin D deficiency and clinical depression in children and adolescents. .. View More»
DOI:
10.35248/2161-0487.24.14.470