ISSN: 2572-0775
Department of Pediatrics, College of Medicine, University of Sulaimani, Region of Kurdistan, Iraq
Hayder Fakhir Mohammad and I am a lecturer holding ( CABP, FICMS, DCH ) degree in Pediatrics , teaching in the School Of Medicine at University of Sulaimani in Kurdistan Region, F.R. Iraq. E-mail: hayder.mohammad @univsul.edu.iq; Mobile: +964(0)7701503429
Research Article
Profile of Gene Positive Familial Mediterranean Fever in Kurdish Children in Sulaymaniyah City, Iraq
Author(s): Hayder Fakhir Mohammad*
Background: Familial Mediterranean fever (FMF) is a hereditary systemic auto- inflammatory disease affecting people of certain ethnic origins. In Iraq, few studies addressed FMF but none tackled patients’ genotypes. This study was carried out in Sulaymaniyah, Iraq to identify the demographic, clinical, laboratory and genetic characteristics of FMF in Kurdish children. Methodology: Sixty-four gene-positive FMF children were prospectively studied over 9-years starting at Jan 2011. Parameters analysed were age, sex, symptoms’ onset-diagnosis interval (SO-DI), symptoms, family history and parents’ consanguinity. Mediterranean fever (MEFV) gene mutations were analysed via real time PCR. Results: There were 41 (64.1%) males. Age ranged between 23 months to16 years with a mean of 7.8 year. Parents were consanguineous in 32.8% and family history was positive in 46.9%. The av.. View More»
DOI:
10.35248/2572-0775.20.5.167