ISSN: 2157-7064
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Dr, Department of Clinical Pharmacology, National Institute for Research in Tuberculosis, Chennai, India
Hemanth Kumar AK is currently working as Scientist D & Head in Department of Clinical Pharmacology, National Institute for Research in Tuberculosis, Chennai, 600 031, India,
Short Communication
A Simple and Sensitive High Performance Liquid Chromatographic Method for Estimation of Transitmycin in Plasma
Author(s): Hemanth Kumar AK*, Jagdeesh B and Sudha V
A high performance liquid chromatographic method for estimation of Transitmycin (Tr) in human plasma was developed. The analyte was extracted using solid phase cartridges and the analysis of the eluent was carried out using Atlantis T3 column (150 cm × 4.6 mm ID) and photo diode array detector set at wavelength of 214 nm. The assay was specific for Tr and linear from 0.5 µg/mL to 20.0 µg/mL. The relative standard deviations for intra- and inter-day assays were less than 10%. The method yielded a recovery for Tr that ranged from 94% to 107% and could be used in toxicology and pharmacokinetic studies... View More»
DOI:
10.35248/2157-7064.20.11.425