ISSN: 2155-9554
+44 1478 350008
Department of Dermatology and Radiology, Shiraz University of Medical Sciences, Shiraz, Iran
Perspective
A Brief Note on Hidradenitis Suppurativa
Author(s): Hiraku Shamir*
Hidradenitis Suppurativa (HS) also known as the acne inversa is a chronic inflammatory skin disorder characterized by deep nodules and lesions such as abscesses, fibrous scars. These lesions are most common in the interstitial and apocrine gland-rich areas. The most common are the axilla, groin, perianal, and perineum. Treatment depends on severity and may include topical and systemic antibiotics, hormone therapy, immune modulators, and surgery. Due to associated pain, tenderness, secretions, odours and scarring this condition can have psychosocial adverse effects. The pathological process of HS begins when a defective hair follicle occludes and ruptures, causing contents such as keratin and bacteria to spill into the surrounding dermis. A chemotactic inflammatory response by surrounding neutrophils and lymphocytes can lead to the formation of abscesses and subsequent destruction of s.. View More»
DOI:
10.35248 /2155-9554.22.13.602