Journal of Thyroid Disorders & Therapy
Open Access

Department of Clinical Laboratory Medicine, Hyogo Medical University School of Medicine, Nishinomiya, Japan

Biography

Dr. Hiroe Konishi is a researcher in the Department of Clinical Laboratory Medicine at Hyogo Medical University School of Medicine in Nishinomiya, Japan. Her research focuses on immunology, particularly the role of adenosine receptors in inflammatory diseases. Academic Background and Affiliation: • Hyogo Medical University School of Medicine, Nishinomiya, Japan: Dr. Konishi is affiliated with the Department of Clinical Laboratory Medicine, engaging in research related to clinical diagnostics and laboratory medicine. Research Contributions: Dr. Konishi has co-authored several publications on inflammatory diseases and adenosine receptors, including: 1. "Adenosine Inhibits TNFα-Induced MMP-3 Production in MH7A Rheumatoid Arthritis Synoviocytes via A2A Receptor Signaling" Journal: Scientific Reports Summary: This study investigates the anti-inflammatory effects of adenosine in rheumatoid arthritis, highlighting its potential therapeutic applications. "Autoantibodies as Biomarkers in Thyroid Diseases" Journal: Journal of Thyroid Disorders & Therapy Summary: This review explores the potential of autoantibodies as diagnostic and prognostic biomarkers in various thyroid diseases.

Publications

• Review   
  Autoantibodies as Biomarkers in Thyroid Diseases
  Author(s): Masayoshi Nakano*, Ayako Miyazaki, Hiroe Konishi, Rika Yukimatsu, Toru Watanabe and Masahiro Koshiba
  
  Thyroid diseases are common pathologies in primary care settings, and many patients with such diseases are treated by physicians who are not specialized in thyroid conditions. To diagnose such diseases earlier, some biological biomarkers have been identified. Anti-TSH receptor antibodies, which are considered the cause of Graves’ disease, are autoantibodies that bind to TSH receptors and activate the thyroid gland. The measurement of anti-TSH receptor antibodies is crucial for diagnosing, managing, and monitoring the treatment of Graves’ disease. This test has high sensitivity and specificity as a diagnostic tool. Conversely, antibodies against the TSH receptor do not have just one property; thus, the anti-TSH receptor antibody assay system could be improved to distinguish the different functions of antibodies. Patients diagnosed with thyroid disorders can generate TSH rec.. View More»
  DOI: 10.35248/2167-7948.23.12.295

  Abstract HTML PDF

Other relevant publications from this author

• Autoantibodies as Biomarkers in Thyroid Diseases

  Adenosine inhibits TNFα?induced MMP?3 production in MH7A rheumatoid arthritis synoviocytes viaA2A receptor signaling