ISSN: 2155-9570
Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Case Report
Systemic Sarcoidosis Mimicking Cogan's Syndrome: A Case Report
Author(s): Elahe Havashki, Mehran Zarei-Ghanavati, Hoda Kavosi, Zohre Ebrahimi, Sanaz Naybandi and Nazanin Ebrahimiadib*
Purpose: To report a case of non-pulmonary sarcoidosis involving cornea and cranial nerve VIII
Case: A 25-year-old lady initially presented with flu-like symptoms, erythema nodosum and polyarthritis of minor
joints. She later developed abdominal lymphadenopathy and splenomegaly. Spleen biopsy revealed granulomatous
inflammation. There was a chronic ocular inflammation due to interstitial keratitis, which responded partially to
topical corticosteroid and tacrolimus. Corneal infiltrations healed with the aid of immunomodulatory agents. Later,
she developed neurosensory hearing loss due to inflammation of Cranial Nerve (CN) VIII. All her symptoms except
neurosarcoidosis has improved with systemic azathioprine, and then oral methotrexate and subcutaneous anti TNF
alpha.
Conclusion: Interstitial keratitis .. View More»
DOI:
10.35248/2155-9570.22.13.912