Immunogenetics: Open Access
Open Access
+44 1223 790975
+44 1223 790975
Department of General Surgery, Jinan Nanjiao Hospital, Jinan, Shandong, China
Research
Mucinous Content is an Independent Prognostic Parameter for Patients with Stage I-III Colorectal Cancer: A Retrospective Study
Author(s): Xiaolin Ji, Hongsheng Ji, Tao Mao, Xiaoyu Li, Minghan Ren, Jie Wu, Suzhen Wang, Yuning Chu and Zibin Tian*
Purpose: High mortality and high heterogeneity are main characteristics of colorectal cancer, whose prognostic predictive indexes are not clear enough. This study aims to elucidate the value of mucinous content as a prognostic parameter for stage I-III colorectal cancer patients.
Methods: This was a retrospective study of 3,852 patients with stage I-III colorectal adenocarcinoma, adenocarcinoma with mucinous content, and mucinous adenocarcinoma (grouped by their mucinous content, 1% and 50% was the cutoff) who underwent curative surgery. Survival curves were plotted by the Kaplan-Meier method, and the differences were evaluated by the log-rank test. Multivariate analyses of oncological outcomes were performed by the Cox proportional hazard model to determine whether mucinous content can independently predict prognoses after corrections. The .. View More»
DOI:
10.35248/IGOA.22.7.176