Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Department of Pharmacology, Faculty of Pharmacy, Wad Medani, Sudan
Research Article
Gastro-protective Effects of Green Banana (Musa cavendishii Lamb.) Pulp Powder on Aspirin-induced Gastric Ulcer in Albino Rats
Author(s): Motasim A Mohammed, Amna E El-Hadi, Esmat A Mohammed, Fatima S Abbas, Khadiga O Musa, Mustafa Y Al-Ameen, Alia M Ahmed, Mona Timan Idriss Gassab, Hozeifa M Hassan and Abdelgadir A Abdelgadir*
Green banana (Musa cavendishii) is used in the traditional medicine in Sudan to treat peptic ulcer disease. The aim of this study was to evaluate the gastro-protective effect of aqueous extract of green banana pulp powder on aspirin-induced ulcer in albino rats. The effect was studied using aspirin-induced gastric damage in rats and compared between groups which were: group 1 (negative control) received water only, group 2 (positive control) received aspirin. Groups 3 and 4 were received 0.5 g/kg and 1 g/kg of banana extract before aspirin 100 mg/kg, respectively. Groups 5 and 6 were received 0.5 g/kg and 1 g/kg of banana extract of banana extract after aspirin 100 mg/kg, respectively. The results indicate that there was a significant difference (p<0.05) in ulcer index between M. cavendishii extract treated groups 3, 4, 5, 6 with ulcer index (15.0 ± 1.31), .. View More»
DOI:
10.35248/2167-0412.21.10.367