Medicinal & Aromatic Plants
Open Access

Laboratory of Transmissible Diseases and Biologically Active Substances, Faculty of Pharmacy, University of Monastir, rue Avicenne, Monastir 5000, Tunisia

Publications

• Research Article   
  Application of Simplex-Centroid Design Methodologies to Optimize the Anti-bacterial and Anti-candidal Activity of the Mixture of Mentha pulegium, Pituranthos chloranthus and Thymus algeriensis Essential Oils
  Author(s): Zoubeyda Souiy*, Ameur Elaissi, Ibrahime Jlassi, Wala Sghair, Noureddine Allouch, Maha Mastouri and Boubaker Krifia
  
  This work aims to study the antimicrobial activities of the essential oils of M. pulegium, P. chloranthus and T. algeriensis and to identify the antagonistic or synergistic impacts of their combinations. Antimicrobial activities were analyzed by disc diffusion and microdilution against six foodborne microbial strains (Staphylococcus aureus, Bacillus cereus, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa and Candida albicans). That's why, to predicate the optimal mix, we are using the Augmented Simplex Centroid Design. The chemical composition shows that the main compound of M. pulegium were pulegone (50.31%) and menthone (26.92%). For P. chloranthus EO, The major constituents were dillapiole (13.56%) and pregnane (8.47%) and the main products of T. algeriensis EO are Camphor (14.0.. View More»
  DOI: 10.35248/2167-0412.21.10.365

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