ISSN: 1745-7580
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Centre for Immunogenetics and Virology, Fundeni Clinical Institute, Bucharesct, Romania
IIeana Constantinescu is affiliates from the carol davila university of Medicine and Pharmacy, Bucharest, Romania. Author was also worked in centre for Immunogenetics and Virology, Fundeni Clinical Institute, Bucharesct, Romania
Review Article
Gastrointestinal Microbiota Impact on the Development of Food Allergy Immune Phenotype
Author(s): Ileana Constantinescu* and Roxana Sfrent-Cornateanu
Recent technological advances have allowed researchers to more accurately describe gastrointestinal microbiota
composition and its interaction with the host in health and disease. Lifestyle changes, including the large-scale use of
antibiotics, alter both the composition and function of the intestinal microbiome, which predisposes the host to
gastrointestinal and metabolic disease, as well as immune system dysfunction.
The purpose of this review is to highlight some key concepts pertaining to the interaction between the gut
microbiome and host, as well as to illustrate how this interaction influences immune system programming, more
specifically, its impact on the development of the immune phenotype characteristic for food allergy.
The following discussion will be about the role of the gastrointestinal microbiota, as one of the many factors which
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DOI:
10.35248/1745-7580.20.16.174