Enzyme Engineering
Open Access

Department of Food Science and Technology, University of Calabar, Calabar, Nigeria

Publications

• Research Article   
  Effect of Sudan II Adulteration of Palm Oil on the Serum Enzyme, Bilirubin Concentration and Renal Function Biomarkers of Albino Wistar Rats
  Author(s): Henry E Peters*, Aniekan S Henshaw, Christine A Ikpeme and Ima-obong Williams
  
  Aim: This study investigated the impact of Sudan II adulteration of palm oil on serum enzymes (ALT, AST, ALP), bilirubin and renal function biomarkers (creatinine, urea) of albino wistar rats. Methods: A total of sixty (60) 750 mL bottles of red palm oil were purchased from random markets in Nigeria. Sixty (60) male albino rats weighing 150-180 g were divided into 5 groups of 12 rats each. Group 1 served as normal control. Groups 2 to 5 were fed 90% rat chow supplemented with 10% red palm oil. The Sudan II dyes were co- administered with the red palm oil with the diet (rat chow) to provide levels of 0.025% (PO/0.025) (group 3), 0.03% (PO/0.03) (group 4) and 0.04% (PO/0.04) (group 5) for a period of 30 days (short term) and 90 days (long term). Animals were sacrificed and blood was collected via cardiac puncture for biochemical analy.. View More»
  DOI: 10.35841/2329-6674.22.11.1000176

  Abstract HTML PDF