Journal of Cancer Research and Immuno-Oncology
Open Access

Department of Medicine, "Titu Maiorescu" University, Bucharest, Romania

Biography

Popescu studied medicine at Carol Davila University of Medicine and Pharmacy in Bucharest and graduated in 1977.He became a Specialist Surgeon in 1983, and in 1990 he became a General Surgeon, getting a PhD from Carol Davila University Bucharest. In 1997, Popescu, along with a group of other scientists, established Romtransplant, a professional organization for raising awareness of the importance of organs transplantation through several arranged national congresses.He teaches in the Faculty of Medicine of Carol Davila University of Medicine and Pharmacy.

Publications

• Research   
  The Immune Response in Gastrointestinal Stromal Tumors
  Author(s): Vlad Herlea*, Alexandra Rosulescu, Andreea Iorgescu, Simona Olimpia Dima, Traian Dumitrascu, Vladislav Brasoveanu, Cezar Stroescu, Catalin Vasilescu and Irinel Popescu
  
  Background: Gastrointestinal stromal tumors (GISTs) are the most frequent tumors with mesenchymal origin at the level of the digestive tract. Assessment of intratumoral immune cells can provide valuable prognostic information and may contribute to the development of targeted immune therapies for selected cases. Here in we evaluated the inflammatory infiltrate in gastrointestinal stromal tumors, the ratios between cytotoxic and helper T cells and their prognostic significance. Methods: We retrospectively analysed 25 cases of GISTs and extragastrointestinal stromal tumors (EGISTs). Immunohistochemical testing for CD3, CD4, CD8, CD20 and CD68 was performed to emphasize the immune cells. Inflammatory cells were quantified with the help of ImageJ software. Statistical analysis was performed to search for correlation between the.. View More»
  DOI: 10.35248/2684-1266.20.6.125

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