Journal of Probiotics & Health
Open Access

Department of Dermatology, Case Western Reserve University, Center for Medical Mycology,University Hospitals Cleveland Medical Center, Cleveland, USA

Biography

Isham N,His international experience includes various programs, contributions and participation in different countries for diverse fields of study. His research interests reflect in his wide range of publications in various national and international journals. He is the Editorial Board Member of Journal of Probiotics and Health. His main research topic and research interest include Probiotics, Dietary regimen, Prebiotic sources etc

Publications

• Research   
  The Probiotic BIOHM Improves Nutrient Absorption by Disrupting Gastrointestinal Biofilms
  Author(s): Ghannoum M*, Ghannoum A, Hager C, Retuerto M, Isham N and McCormick TS
  
  Aim: To demonstrate the ability of a probiotic supplement (BIOHM) to disrupt pathogenic gastrointestinal biofilms, thus enhancing nutrient absorption. Methods: A filter insert model using Caco-2 cells to mimic an intestinal monolayer was employed to determine the ability of BIOHM to disrupt a mixed species (Candida tropicalis, Escherichia coli and Serratia marcescens) biofilm known to occur in patients with Crohn’s disease. Penetration of vitamin C and casein as representative of vitamins and proteins, respectively, was then measured. Results: Application of BIOHM led to a significant increase in casein penetration through the Caco-2 cell epithelial monolayer in the absence of biofilms (p value<0.0001). Additionally, the combination of mixed species biofilms grown on a Caco-2 cell monolayer with BIOHM filt.. View More»
  DOI: 10.35248/2329-8901.19.7.213

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