Journal of Leukemia
Open Access

Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland

Biography

Izabela Dere?-Wagemann graduated from medical studies at the Medical Faculty of the Medical Academy in Wroc?aw. He is a hematologist and specialist in internal medicine. She obtained the PhD degree in medical sciences in 2016 on the basis of a distinguished doctoral dissertation thematically related to the treatment of acute leukemia. His clinical experience is based on work in the hematology department, hematology clinic, bone marrow transplantation unit and work in the office. He has professional experience related to bone marrow transplants, the qualification of bone marrow donors and transfusion medicine.

Publications

• Research Article   
  Primary and Secondary Central Nervous System Involvement in Acute Myeloid Leukemia
  Author(s): ElÃ?¼bieta Patkowska*, Andrzej Szczepaniak, Marta Barańska, Maciej Kaźmierczak, Monika Paluszewska, Wiesław Wiktor Jędrzejczak, Renata Guzicka-Kazimierczak, Wanda Knopińska-Posłuszny, Olga Grzybowska-Izydorczyk, Agnieszka Pluta, Jarosław Piszcz, Izabela Dereń-Wagemann, Ewa Lech-Marańda and Joanna Góra-Tybor
  
  Introduction: Central Nervous System involvement (CNSi) in patients with Acute Myeloid Leukemia (AML) rarely occurs. It is not well characterized clinically and lacks standardized treatments. Patients and methods: A retrospective analysis of 77 consecutive AML patients with primary and secondary CNSi during 2004-2016 was performed in eight Polish haematological centres. Results: 77 patients (38 with primary CNSi-AML) were included. Median age was 44 years in both groups. Elevated lactate dehydrogenase activity was found in the majority of subjects. Patients in primary CNSi-AML group more often had myelomonocytic and monoblastic AML subtypes (68.4%) compared to secondary CNSi AML (43.5%) (p=0.039). There were no differences between both groups in the number of leukocytes or the proportion of blast cel.. View More»
  DOI: 10.35248/2329-6917.19.7.257

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