ISSN: 2475-7586
Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, California, USA
Original Research Article
Modeling and Simulation for Identification of Possible Cause for Portal Vein Thrombosis: A Complication of Sleeve Gastrectomy
Author(s): Ara Keshishian*, Jaehoon Lee and Santiago Salgado
Background: This study was performed to study possible causes of Portal Vein thrombosis, a potentially deadly
complication of specific foregut surgical procedures.
Methods: Mathematical models of blood flow to the foregut organs, stomach, duodenum, spleen, and liver, were
created in MATLAB. Pathologic conditions were created by removing or adding the electrical components in the
circuit modeled in MATLAB. These modifications represented surgical variation and hemodynamic changes.
Comparing the input and output waveforms and comparing them to the known wave from live subject samples were
able to model conditions where the likelihood of portal vein thrombosis is most likely to occur.
Results: Ligation of the gastroepiploic vessels produce significant flow disruption in our model, significantly more
than.. View More»
DOI:
10.35248/2475-7586.22.07:241