ISSN: 2475-7586
Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA
Jamie Chang completed her PhD from U.C. San Francisco in Medical Sociology where she conducted research on homelessness and drug/alcohol use. She has been involved with the research and evaluation of substance use treatment programs in medical and community settings, including County Departments of Public Health, V and the substance use treatment experiences of people who are homeless.Recently, Chang’s has led a multi-method approach to documenting and analyzing the increasing number of people who are homeless dying in Santa Clara County. Her lab developed the SCC Unhoused Death website as a research tool that can increase public awareness.
Research
Validation of a Novel Noxious Pressure Device for Use in fMRI Pain Studies
Author(s): Marisa DiMarzio, Michael Spinrad, Maria Hancu, Ellinor Grinde, Jamie Chang, Julia Slyer, Michael Gillogly, Julia Prusik, Julie G. Pilitsis*, Eric Fiveland and Ileana Hancu
Background: Most fMRI studies on pain perception utilized thermal stimuli due to the lack of a non-metallic reliable, reproducible mechanical stimulus. We explored 2 potential MR compatible mechanical devices and validated one that induced changes on fMRI.
Purpose: To validate a noxious mechanical stimulus MR compatible device in a healthy cohort and a chronic pain cohort. Further to ensure this device caused changes on fMRI compared to a pressure device.
Methods: Two-healthy controls underwent fMRI scans in the presence/absence of mechanical noxious stimuli using different devices. A paradigm for administering the stimuli with the most robust responses on fMRI was developed. Reproducibility of the device was confirmed in 10 chronic pain patients and age/gender-matched healthy controls. Comparisons of patient demog.. View More»
DOI:
10.35248/2475-7586.19.4.138