International Journal of Physical Medicine & Rehabilitation
Open Access

Department of Physical Medicine, Era’s Lucknow Medical College and Hospital, Lucknow, India

Publications

• Research   
  Decoding Oxidative Stress and Anti-oxidative Parameters in Patients with Spinal Cord Injury
  Author(s): Jan Fedacko*, Ammar Mehdi Raza and Najah R Hadi
  
  Introduction: In this study we evaluated the connivance of oxidative and anti-oxidative parameters in the pathogenesis of Spinal Cord Injury (SCI). Although the etiology and pathogenesis of SCI remain to be fully understood, it has been suggested that Reactive Oxygen Species (ROS) and oxidative stress may play a significant role in the pathophysiology of SCI. Furthermore, there is little information available in scientific literature about oxidative and anti-oxidative parameters in SCI patients. Methods: Oxidative stress was determined by measuring the levels of Lipid Peroxides (LPO) and Protein carbonyl in plasma and anti-oxidative parameters like Glutathione Reductase (GR), catalase and Glutathione Peroxidase (GPx) in lysate in 40 SCI patients and 40 healthy subjects without SCI. However, pain was measured by McGill pain questionnaire... View More»
  DOI: 10.35248/2329-9096-22.10.625

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