Virology & Mycology
Open Access
ISSN: 2161-0517
ISSN: 2161-0517
Los Alamos National Laboratory, Biosecurity & Public Health, Los Alamos, USA
Dr. Fair, was on assignment as a Regional Science Manager with the Cooperative Biological Engagement Program (CBEP) in the Cooperative Threat Reduction (CTR. Dr. Fair led the initiative for Middle East and Central Asia region to develop research projects that address infectious diseases priorities for CBEP and partner countries.
Research Article
Whole Genomes of Avian orthoavulavirus 1 (Newcastle Disease Virus Genotypes VIg or new genotype XXI.) in Wild Birds in Kazakhstan
Author(s): Vitaliy Strochkov, Yerbol Burashev, Nurlan Sandybayev, Gang Xie*, Tracy H. Erkkila, Helen Cui and Jeanne M. Fair*
Background: The remarkable diversity and mobility of Newcastle disease viruses (NDV) includes virulent viruses of
genotype VI. These viruses are often referred to as pigeon paramyxoviruses 1 because they are normally isolated and
cause clinical disease in birds from the Columbidae family. Genotype VI viruses occasionally infect, and may also
cause clinical disease in poultry. Thus, the evolution, current spread and detection of NDV are relevant to avian
health.
Methods: Nucleotide sequencing and phylogenetic studies of three Kazakhstan isolations were performed to
characterize the complete fusion (F)-protein gene as well as whole genome sequence. Sequence data were compared
with 106 Fusion genes representing different NDV genotypes and sub-genotypes, as well as 225 fusion genes and 37
whole genome of class VI NDV strains from different regions of the world.. View More»
DOI:
10.35248/2161-0517.20.09.183