Advances in Pediatric Research
Open Access
ISSN: 2385-4529
ISSN: 2385-4529
Division of Pediatric Intensive Care, Department of Pediatrics, Hospital das Clínicas Foundation Gaspar Viana, Belém, Brazil
Research Article
Hospitalized Children with Critical SARS-CoV-2 Infection Cared in a Limited Resource Setting: Multicenter Cohort Study
Author(s): Rafaella R. Gomes, Maria C.A. Justino, Kathia de O. Harada, Jessica L. Alves, Renata de B. Braga, Patricia B. Carvalho, Mary L.F. M.F. de Mello, Salma B. Saraty, Cristiane T.C. Silva, Railana D.F.P. Carvalho, Gabriela C.L. Pontes, Adriana MB de Sousa, Gabriella M. Galvão, Sara M.P. de Moraes, Emmerson C.F. de Farias*, Michaelle J.D. Serrão, Mayara M.M. Machado, Luana G. Dias, Carina C. Costa, Larisse F.Q. Aires, Kíssila M.M.M Ferraro, Marília C.B. Alves, Andreza H.O. Pinheiro, Valeria T.S. dos Santos, Dalila C.A. Pavão, Luciana M.P.P. do Nascimento, Susan C.D. de Sales and Manoel J.C. Pavão
Background: Some children can develop severe forms of SARS-CoV-2 infection either acutely or later, as represented by Multisystemic Inflammatory Syndrome in Children (MIS- C). To identify the risk factors for worse outcomes in hospitalized children and adolescents with severe acute SARS-CoV-2 infection and MIS-C.
Methods: This multicenter cohort study included all children and adolescents with confirmed or suspected critical SARS-CoV-2 infection admitted to the Pediatric Intensive Care Unit (PICU) between April 2020 and September 2021. The exclusion criteria were incomplete vaccinal status, immune-compromised status, and end-of-life decision. The main variables analyzed were epidemiological, clinical, and laboratory data, and ventilator settings at admission and after 72 h. The patients were divided into three groups (G): confirmed coronavir.. View More»
DOI:
10.35248/2385-4529.23.10.052