Journal of Leukemia
Open Access

Department of Hematology, Union Hospital, People's Republic of China

Biography

Dr. Jianda Hu is an Associate professor in the Department of Hematology, Union Hospital, Fujian Medical University, China. Currently, Dr. Jianda Hu is the author/editors/reviewer in several international journals. He contributed in 140 articles of many journals and the articles are informative and got good citations.

Publications

• Review Article   
  Treatment Advances for Burkitt Lymphoma
  Author(s): Issa Hajji Ally, Ting Yang* and Jianda Hu
  
  Burkitt Lymphoma (BL) is an uncommon but highly aggressive B-cell Non-Hodgkin Lymphoma (NHL). It is a subtype of mature B-cell lymphoma and can be treated successfully within a short period via high-intensity chemotherapeutic regimens. Diagnosis and initial work-up must be completed rapidly to begin treatment due to high proliferation. BL is associated with the Epstein-Barr Virus (EBV) and with a chromosomal translocation that activates the c-MYC gene. However, by implementing chemotherapy regimens, complete remission and overall survival for young patients with BL remains high. In contrast, in elderly patients and those with relapsed/refractory disease, the prognosis remains a medical challenge. Rituximab, the chimeric monoclonal antibody against CD20, has improved the clinical management of B-cell malignancies. Because BL expresses a CD20 positive marker in their cell surface.. View More»
  DOI: 10.35248/2329-6917.19.7.255

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