ISSN: 2684-1266
+44-77-2385-9429
Department of Radiation Oncology, Sheba Medical Center, Ramat Gan, Israel
Research Article
Prediction of Local Failure for Post-Operative Radiotherapy of Resected Brain Metastases in Breast Cancer Patients
Author(s): Jie Feng*, Glassner Saechs, Rachel Patel, Piang Liang and Nicolas Guieu
Single brain metastasis surgical resection remains an effective treatment for brain metastases. However, surgery
alone associate with a high rate of local failure. The current guidelines recommend radiation to surgical cavity.
The recommended dose for brain cavity after surgery remain to be define as most guidelines gives a very general
suggestion about the dose and fractionation. The aim of this study was to determine what variable influence local
control in this specific population. Methods Retrospective analysis of 52 patients with breast cancer who undergo
surgical resection to single brain metastases and who received post-operative radiotherapy between the years 2010-
2022. All clinical and dosimetric variables were analyzed to evaluate their impact on local control. A predictive
model for local control was calculated. Results One year local control was 65.3.. View More»
DOI:
10.35248/2684-1266.23.09.197