International Journal of Physical Medicine & Rehabilitation
Open Access
ISSN: 2329-9096
+44 1300 500008
ISSN: 2329-9096
+44 1300 500008
Department of Pediatrics, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China
Dr. Jieqin Song is an Assistant Professor in the Department of Pediatrics, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China. His research interest includes Speech Science, Hearing Science, etc. He has published more than 10 publications and the articles are informative and got good citations.
Mini Review
Function of Bile Acid Associated with Gut Microbiota
Author(s): Jieqin Song, Hongwei Hu, Meng Li, Jingjing Xiong, Mei Liu and Yongkun Huang*
The human gut microbiota involve in metabolism of carbohydrates, proteins and bile acids. Primary bile acids Cholic acid (CA)
and Chenodeoxycholic acid (CDCA) are synthesized in the liver and conjugated with the amino acids glycine or taurine, stored in
the gall bladder. Glycine and taurine conjugates of CA and CDCA are transformed into the secondary bile acids deoxycholic acid
(DCA), lithocholic acid (LCA) and a small amount of urosodeoxycholic acid (UDCA) by microbiol actions. The bile acids have
a unique relationship with the gut microbiota. Although a great deal of work has shown that different bile acids play different
roles in maintaining the intestinal barrier according to their uniqueness, the underlying mechanisms are complex and need to
be further studied... View More»
DOI:
10.35248/2329-9096.21.9.587