Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Basic Medicine, Bengbu Medical College, Anhui, China
Research Article
A Novel Cuproptosis-Related LncRNA Signature Predicts Prognosis in Patients with Esophageal Carcinoma
Author(s): Shang Peng, Haipeng Li, Jingting Min, Ran An, Nana Du and Zhenghong Li*
Introduction: Esophageal Cancer (ESCA) is a significant cause of tumor-related mortality worldwide. Cuproptosis
is a novel cell death which is different from other regulate cell death, including ferroptosis, pyroptosis and apoptosis.
However, the role of cuproptosis in the initiation and progression of ESCA remains unknown.
Materials and methods: The transcriptome data and clinical data of 173 patients with esophageal cancer in The
Cancer Genome Atlas (TCGA) database were sorted and extracted with Perl software. Pearson correlation analysis
was performed on cuproptosis related genes and all LncRNA’s. The prognostic related LncRNA’s were determined
by univariate and multivariate Cox regression analysis, and a new prognostic model was constructed to calculate
the risk score of each patient. C-Index curve, Principal .. View More»
DOI:
10.35248/2167-0870.23.13.542