Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Physiology, University of Abuja, Gwagwalada, FCT, Nigeria

Publications

• Research Article   
  Ivermectin is Associated with Increase in SPO₂ in Hypoxemic SARS-CoV-2 Patients: Pharmacodynamic Profile and Correlates
  Author(s): Babalola OE*, Adesuyi Ajayi, Thairu Yunusa, Yahaya Abdullahi Ndanusa, John Ogedengbe and Ogu Omede
  
  Background and objectives: Hypoxemic respiratory failure is a common mode of demise in COVID-19 disease. We aimed to describe the time course of SPO2 changes in COVID-19 patients treated with and without ivermectin. Methods: This was a parallel group, prospective comparative study of propensity matched COVID-19 patients (Cycle threshold Ct<25, SPO2<94%). 21 of the patients received Ivermectin (IVM) inclusive regime at 12 mg daily for 5 days, while 26 others received Non-ivermectin Inclusive Regime (NIVM). Results: The IVM group demonstrated earlier and greater increase in SPO2 (p=0.000) which paralleled greater and faster virological clearance (p=0.000) on Repeat measures Analysis of Variance RMANOVA. There was a significant correlation between absolute SPO2 and abs.. View More»
  DOI: 10.35248/JCCLM.22.5.222

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