Transcriptomics: Open Access
Open Access
ISSN: 2329-8936
ISSN: 2329-8936
Department of Genomics of Complex Disease, Research Institute of Sant Pau Hospital, Barcelona, Spain
Research Article
Transcriptome Analysis in Response to Endurance Exercise in Non-Elite Marathon Runners
Author(s): Pol Ezquerra Condeminas*, Laura G. Antiga, Jan Borras Ros, Antonio Cardenas, Oriol Sibila, Alexandre Perera-LLuna and Jose Manuel Soria
Objective: Given that endurance exercise can have a huge impact on nonelite athletes, this study set out to analyze
differentially expressed genes and pathways before and after a marathon, then subsequently assess which body systems
may be deregulated during such activity.
Methods: The study included 60 nonelite athletes (42 men and 18 women) participating in the Barcelona Marathon. Blood samples were extracted at three different time points: before the marathon at baseline levels (START), immediately upon completion (FINISH), and 24 hours after its completion (24REST). Differential gene expression, GO term, and KEGG pathway analyses were conducted on the samples from each of the groups and three different comparisons made: C1 (START vs. FINISH), C2 (FINISH vs. 24REST), and C3 (START vs. 24REST).
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DOI:
10.35248/2329-8936.23.9.134