ISSN: 2329-9495
+44 1478 350008
Department of Angiology and Vascular Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain
He is currently working as Specialist in Angiology and Vascular Surgery in Madrid, research focuses on clinical vascular disease, how to find less effective approaches, how to improve the treatment methods and early detection of cardiology.
Research Article
Safety and Effectiveness of a Shortened Regimen of Alprostadil (PGE1) with Large Infusion Dose, for Ischemic Manifestations of the Extremities in Real-World Clinical Practice
Author(s): Teresa Cervera*, José Manuel Ligero and Ana de Lorenzo
Objective: To analyse historical indications, tolerance, secondary effects and effectiveness of a treatment regimen with short interrupted cycles of large doses of PGE1 as well as possible factors that may influence the results in real world clinical practice in a tertiary hospital.
Material and Methods: This is an observational, descriptive, retrospective study of all patients treated from 2013 to 2020 with high-doses of PGE1 in our hospital.
Results: Forty five patients from 27 to 91 years old were treated for ischemic diseases, grouped into 6 types. Treatment caused side effects in 14 patients (31%) and has to be discontinued in 6 of them for intolerance (13% of total). Intolerance was associated with heart disease and advanced age. No short or long term complications were observed in these patients after discon.. View More»
DOI:
10.35248/2329-9495.22.10.299