Journal of Down Syndrome & Chromosome Abnormalities
Open Access

Department of Molecular Biology, Heidelberg University, Germany

Biography

Dr. Joseph Christine is currently working at Molecular Biology, Heidelberg University, Germany. Dr. Joseph Christine has authored over 11 scientific articles, and serves as a reviewer/board member to many national and international journals. He has also attended many conferences. He is also an active speaker at various national and international conferences. He is an active member of various scientific committees.

Publications

• Perspective Article   
  An Overview on Molecular Biology and Genetics of 22q11.2 Deletion Syndrome
  Author(s): Joseph Christine*
  
  The 22q11.2 Deletion condition (22q11.2DS) is an intrinsic contortion and neuropsychiatric issue brought about by meiotic chromosome improvements. One of the objectives of this survey is to sum up the present status of essential examination investigations of 22q11.2DS. It features endeavors to comprehend the instruments answerable for the 22q11.2 erasures that happens in meiosis. This instrument includes the four arrangements of low duplicate rehashes (LCR22) that are scattered in the 22q11.2 district and the erasure is intervened by non-allelic homologous recombination occasions. One more significant part of 22q11.2DS is the presence of phenotypic heterogeneity. While a few patients are somewhat influenced, others have serious clinical, intellectual as well as mental difficulties. Changeability might be expected partially to the presence of hereditary modifiers... View More»
  DOI: 10.35248/2472-1115.21.7.179

  Abstract HTML PDF